The California Department of Public Health said the Sacramento County person may have been exposed while aboard an international flight carrying a passenger who later died from the virus.
The exposure is tied to an outbreak aboard the Dutch cruise ship MV Hondius, where at least 10 cases of Andes hantavirus and three deaths have been reported.
One of the three California residents who was on the cruise ship has returned home and is being monitored in Santa Clara County, health officials said.
"The risk to the public remains extremely low," CDPH said in its latest update.
"We understand public concern about this unusual outbreak," said Dr. Erica Pan, California's state public health officer and CDPH director. "Decades of experience in South America have shown that this Andes hantavirus rarely spreads between people."
Public health officials said exposed individuals are monitored for 42 days under CDC guidance. Monitoring includes daily temperature checks, symptom screenings and activity modifications.
Officials noted that the Andes virus differs from the Sin Nombre hantavirus strain found in California and other parts of North America. The Sin Nombre strain has not been linked to person-to-person transmission.
The CDPH said 99 California residents were diagnosed with Sin Nombre hantavirus infections between 1980 and 2025.
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