Photos of Eric Dane Through the Years: From ‘Grey’s Anatomy’ to ALS Battle ...Middle East

Eric Dane rose to fame in the early 2000s after he was introduced to fans as Dr. Mark “McSteamy” Sloane on Grey’s Anatomy in 2006.

After his (spoiler alert) onscreen death in 2012, the actor moved on from his stint at the Grey Sloan Memorial Hospital and to tackle other roles. While Dane has appeared in several movies over the years, various TV series have defined the bulk of his career. The actor starred as Tom Chandler on The Last Ship from 2014 to 2018 before taking on Cal Jacobs on Euphoria, a role he’s held since 2019.

Dane’s personal life has also made headlines throughout his career, including many ups and downs with wife Rebecca Gayheart. In April 2025, Dane — age 52 at the time — announced that he had been diagnosed with ALS. He died less than one year later.

Keep scrolling to look back at the actor through the years:

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