The 49ers (6-3) did that for the first time all season last week against the New York Giants and will have a far more difficult time pulling it off again on Sunday, when they host the Los Angeles Rams (6-2) and one of the NFL's stingiest defenses in a key NFC West showdown.
The San Francisco 49ers celebrate after recovering a fumble during the game against the Los Angeles Rams at SoFi Stadium on October 2, 2025, in Inglewood, California. The 49ers defeated the Rams 26-23. Michael Zagaris/San Francisco 49ers/Getty Images"Why not 40? Or score 50 a game," McCaffrey said. "Football's funny because sometimes when guys get hurt, people act like there's a new level of urgency that has to come. There's always a high level of urgency in this game, whether or not you got all your dogs or not. It's a violent game and you have to come every Sunday with a certain mindset. That's the way I approach it."
"Yeah, it'll be Mac again starting," said Shanahan. "I haven't decided whether to make [Purdy] active or not, but he's further along this week than last week."
Warner played a big role that night in his final full game before going down with an ankle injury, making 12 tackles and helping stop a fourth-and-1 try in overtime to seal the win.
"Any time you take Fred off the field, it's going to be different for sure," receiver Davante Adams said. "They're still the defense that they are. It's the way that they're coached. It's the way that Fred has led them to be over there. No matter who's in there, we expect them to be able to play the same brand of football. Maybe not exactly like Fred would play, but guys are still going to be flying around."
The 49ers have remained in contention despite a run of injuries in large part because of the play of Jones at quarterback. The former first-round pick by New England in 2021 has had a career rebirth in his first season in San Francisco, making seven starts this season with Brock Purdy out with a toe injury.
The Rams had to go to overtime with San Francisco last month in no small part because Joshua Karty missed a long field goal in the third quarter before the 49ers blocked his extra-point attempt with 10:39 to play. After an NFL-high eight missed or blocked kicks this season, the Rams finally started to do something about it this week, signing kicker Harrison Mevis and long snapper Jake McQuaide to their practice squad amid a heavy emphasis on special-teams preparation in meetings and practice.
"I think making kicks and not getting a punt blocked are usually the biggest things that stick out the most, or giving up a big return," Shanahan said. "You can play really good special teams and if any one of those three things happen on just one play, then it's catastrophic special teams."
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