The 78-year-old, originally from Dodge City, Kansas, lives in North Hampshire with his wife Rita. He was diagnosed with mild cognitive impairment in 2018 after having problems with his memory and difficulties absorbing information.
Larry – who met his wife in Boston in 1970 while they worked in the same hospital – is one of just a few people in the UK who have had access to lecanemab via a clinical trial, which he is due to complete at the end of 2025.
Larry, who moved to the UK in 1977, said: “Everyone when they get old forgets things, like why did you go into that room or what channel is that show on. But my memory had slipped a little bit more than normal.
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Lecanemab was given a UK licence last year but was not approved for use on the NHS by the spending watchdog, the National Institute for Health and Care Excellence (Nice), which deemed the drug not cost-effective.
Rita said: “We feel fortunate that Larry’s diagnosis came so early and got us on this journey at a time when he could be helped. And we feel fortunate that he has received a drug that is beneficial.
“We hope that now there are treatments that are proven to slow down this disease, it will bring Alzheimer’s out of the shadows. We hope it will encourage people when they first notice a problem to seek help and get a diagnosis.”
About one million people in the UK are living with dementia, of which Alzheimer’s is the most common form, and this is projected to rise to 1.4 million in 2040.
Rita said: “I think to contribute to any drug trial is a gift to research. Not every drug trial is going to be beneficial, but every trial will tell the researchers something about that drug and help move things forward.
“There are many people in the future who will have this disease. So, the sooner we get to a cure the better. The more drug trials that are run, the more people who partake, the faster we will get there.”
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