Kittle injured the hamstring in the first half of the 49ers' season-opening win at Seattle on Sunday after he had caught four catches for 25 yards and a touchdown.
In his place, Jake Tonges and Luke Farrell will handle the tight end duties until at least the Week 6 game against Tampa Bay. Tonges, who grew up in the Bay Area, caught the game-winning touchdown pass on Sunday, his first career TD.
George Kittle #85 of the San Francisco 49ers looks on during the NFL 2025 game between San Francisco 49ers and Seattle Seahawks at Lumen Field on September 07, 2025 in Seattle, Washington. Steph Chambers / Getty ImagesSince signing with the 49ers in 2017, San Francisco has a 64-50 record when Kittle is in the game, versus a 7-12 record when he is out, according to StatMuse. Kittle missed three games in 2024 because of separate hamstring injuries.
Earlier this year, Kittle signed a four-year, $76.4 million contract extension, making him the highest-paid tight end in the league.
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