Birmingham Police said the incident happened near the junction of Yardley Road and Florence Road in Acocks Green, Birmingham, just before 7pm on Wednesday.
The pedestrian was pronounced dead at the scene and his family are being supported. The two officers in the vehicle were not hurt.
Anyone with information, including dashcam or other footage, has been asked to get in touch with police on 101, quoting log 4726 of March 19.
Police added other officers attended the report of the man with the knives, but there was no sign of any disorder on arrival.
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