The new condition, which is caused by genetic mutations, has shown a particularly high death rate, as patients were not responding to any currently available treatments, the researchers said. The disease – ‘vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome’ – has been dubbed VEXAS. It causes symptoms that include blood clots in veins, recurrent fevers, abnormalities in the lungs, and vacuoles – unusual cavity-like structures – in the myeloid cells, which play a crucial part in the human immune system. Researchers at the US National Institutes of Health (NIH) came across the disease after analyzing the genome sequence
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