Linebacker Eric Kendricks will make his 49ers debut Monday night against the Indianapolis Colts as will Jordan James, a fifth-round draft pi...

Philip Rivers and the Indianapolis Colts face Christian McCaffrey and the San Francisco 49ers on Monday Night Football.

Week 16 concludes this evening, with the Colts taking on the 49ers on Monday Night Football.How to Watch Monday Night Football: Colts vs...

The Sleeper promo code NEWSWEEKXL will earn new users a $100 bonus to play on Colts vs. 49ers and NFL games this week.

Monday Night Football brings an interconference matchup that puts the San Francisco 49ers on the road against the Indianapolis Colts. This g...

Week 16 wraps up with a matchup between a playoff team and one trying to keep playoff hopes alive.

New users can score a Kalshi promo code to make trades on prediction markets like Monday Night Football’s matchup between the 49ers and Colt...

It’s time for Monday Night Football!The Colts and 49ers close out Week 16 tonight with playoff implications at stake. Here’s a look at s...

“If they said, you had to do this or die? Yeah, you could pull off something.”

Did anyone actually watch Colts quarterback Philip Rivers play football last week?Checking in with the national media and the hellscape tha...

The San Francisco 49ers are taking on the Indianapolis Colts at 5:15 p.m. PDT on Dec. 22 at Lucas Oil Stadium on Monday Night Football.The...

The San Francisco 49ers (10-4) bring a four-game winning streak into a matchup against the Indianapolis Colts (8-6) on Monday, December 22...

San Francisco 49ers tight end Jake Tonges will match up with the 31st-ranked passing defense of the Indianapolis Colts (247.6 yards allowed...

The San Francisco 49ers (10-4) will visit the Indianapolis Colts (8-6) on Monday at 8:15 p.m. ET. Keep scrolling for DFS analysis.49ers v...

The Colts announced Anthony Richardson's return to practice amid questions at quarterback for the remainder of the season.