Metabolic changes in fat tissue in obesity associated with adverse health effects ...Middle East

A twin study recently completed at the University of Helsinki indicates that the machinery responsible for energy handling in fat tissue is working poorly in obesity. In the study, a clear reduction was seen in the activity of mitochondrial genes in obesity in fat tissue, while similar genome-level change in muscle mitochondria was minor. A link with adverse health effects was identified in the mitochondria of fat tissue only.

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