The tournament co-hosts have won every game so far, without conceding a goal, and boast a ridiculous home record at their iconic Mexico City home.
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So as Monday's monumental tie approaches, what is the latest team news? And how could both sides set up?
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Download your FREE World Cup 2026 wall chart and have every fixture at your fingertips.James is nursing a hamstring issue, though reports suggest he is hoping to be fit for Monday, while Quansah hurt his ankle in the 2-0 victory over Panama and Tuchel has suggested he is making good progress.
Anthony Gordon may get the nod over Marcus Rashford on the left after an impressive impact off the bench in the round of 32.
Mexico v England predicted line-ups
England: Pickford; Spence, Konsa, Guehi, O'Reilly; Rice, Anderson; Madueke, Bellingham, Gordon; Kane
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