The symptoms: The woman had been trying to conceive with her male partner but had not become pregnant. Two rounds of in vitro fertilization (IVF) also failed to produce a pregnancy, but gynecological exams did not find any underlying causes for why she was unable to become pregnant. (When the patient's doctors described the case in a report, they did not mention if any fertility tests were also conducted on her partner.)
What happened next: At the facility, blood tests revealed that the woman had unusually high amounts of eosinophils, a type of white blood cell that defends the body against allergens. Skin tests showed that, in addition to the woman's known allergy triggers, she was sensitive to mites, pollen from weeds and grasses, and allergens from insects and dogs.
In an interview with an allergist at the facility, the patient confirmed that she experienced nasal congestion and sneezing after unprotected intercourse with her male partner. These symptoms were previously overlooked by other specialists during consultations about her inability to conceive, she reported.
Sensitivity to semen "is a potential cause of female infertility," because such allergies can trigger inflammation in reproductive organs, according to the report. It's not immediately clear if the allergy somehow complicated the woman's IVF treatments, as well, given semen would not have been present in the implanted embryos.
The only known treatment for reducing sensitivity to semen involves introducing the fluid into the patient's body in gradually increasing concentrations, to build up their tolerance to the allergens. But this course of treatment was unavailable in Lithuania, the doctors wrote. Instead, they recommended that the woman take antihistamine medication before intercourse to reduce the severity of her allergic reactions.
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The causes of infertility are often difficult to pinpoint. Therefore, "this case serves as a reminder that seemingly unrelated allergic conditions, when combined, can contribute to reproductive health challenges, warranting comprehensive evaluations," the woman's doctors wrote.
This article is for informational purposes only and is not meant to offer medical advice.
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