In a March 2026 interview with Deadline Hollywood, alongside the cast and crew of his upcoming horror comedy film, Drag, Stamos was asked if he'd ever return to play his Full House character, Jesse Katsopolis, better known as Uncle Jesse. Stamos portrayed the rock-and-roll-loving character throughout Full House's eight-season run, which ended in 1995. The 62-year-old actor reprised the role for the Netflix reboot, Fuller House, which ran for five seasons until 2020, per IMDb.
"Saget's passed away now, and he used to do a joke before he died. You can do Fullest House with just me and an urn on the fireplace," said Stamos to Deadline Hollywood.
"After playing this role, I'm never going backward. This is forward. I I mean, you know, this is where I'm at with my career. I did just another show, that's not like this, but in this vein, and that's where I'm going," said Stamos in the March 2026 interview.
John Stamos Shared How He Was Able to Accept That Uncle Jesse Was His Most Recognizable Role
In a 2023 interview on The Howard Stern Show, Stamos suggested he was initially bothered by fans only seeing him as his Full House counterpart. He said, however, he was given some perspective when he worked with late actorJames Earl Jones in the Broadway production of The Best Man in 2012. He referenced that Jones provided the voice for iconic Star Wars villain, Darth Vader.
"One of the moments was when I worked with James Earl Jones and here I am on stage with the greatest living actor. As we're walking out the stage door the first thing I hear, 'Uncle Jesse, Uncle Jesse, say Have Mercy!'" recalled Stamos in the 2023 interview. "And I couldn't look at the guy man. And he was standing next to me and just as I was just ready to throw up, I look over and somebody had their phone and they put it up to James, and said, 'James say Luke I am your father.' And we both looked at each other. I said, 'F--k it. That's it.' I'm never worrying about Uncle Jesse and all that stuff again."
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