Biosafety Review Board (BRB) ...Middle East

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Preparations for Next Moonwalk Simulations Underway (and Underwater) ESA astronaut Alex Gerst working with a BioServe-designed drug metabolism experiment on the International Space Station

The mission of the Biosafety Review Board (BRB) is to identify, evaluate, control and prevent biological hazards in conformance with NASA, federal and international health and safety regulations. The BRB includes a team of microbiologists, cell biologists, physicians, industrial hygienists, and occupational health professionals to assess the wide range of biohazardous materials encountered. Biohazardous materials may consist of bacteria, fungi, viruses, protozoa, cell cultures, and other infectious agents. All biological payloads are assessed and biohazardous materials identified are assigned a NASA biosafety level (BSL). Additional functions of the BRB include evaluating ground-based experiments utilizing biohazardous materials, maintaining a current inventory of biohazardous materials that are stored at JSC facilities, and conducting an annual inspection of JSC facilities utilizing biohazardous materials.

Biosafety Review Board Operations and Requirements Document

This Biosafety Review Board Operations and Requirements Document (PDF, 775KB) establishes requirements for the information needed by the BRB to identify and assess biohazardous materials utilized in payload or ground-based experiments. The document also defines the requirements for tracking biohazardous materials that are stored at JSC facilities and the requirements for inspecting JSC facilities utilizing biohazardous materials. This document supersedes all biological material references in JSC 27472 “Requirements for Submission of Data Needed for Toxicological Assessment of Chemicals to be Flown on Manned Spacecraft”.

How to Submit a Payload Experiment for Biosafety Review

Submission – ISS

For all ISS and Artemis (Orion, Gateway, Human Lander System (HLS)) requests, please submit data via the electronic hazardous materials summary table (eHMST) tool. If you do not have access to this tool, please submit a NAMS request for access to JSC – CMC External Tools.

NOTE: For experimental payloads/hardware planned for launch on a Russian vehicle, stowed and/or operated on the Russian Segment of ISS, or planned for return or disposal on a Russian vehicle, we strongly encourage payload providers to submit biological and chemical data to the Russian Institute for Biomedical Problems (moukhamedieva@imbp.ru or barantseva@imbp.ru) .

Ground Based Experiment for Biosafety Review

Downloadable Form

Ground-Based Data Submittal Form

Feb 26, 2025

XLSX (34.27 KB)

Completed forms are submitted to JSC-microbrb@mail.nasa.gov.

Points of Contact

Mark Ott, PhD, Chairman Biosafety Review BoardStarla G. Thornhill, Ph.D., Executive Officer Biosafety Review Board

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Last Updated Mar 05, 2026 EditorRobert E. LewisLocationJohnson Space Center

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