The promos for episode 6, titled When I Crash, had teased life-threatening danger for Dr Jo Wilson (Camilla Luddington) – with Winston (Anthony Hill) revealing that her heart was failing – and Teddy (Kim Raver), who was seen trapped under a crashed bus.
The situation soon turned from bad to worse when pills didn’t work and an attempt to insert a pump went south, leaving Jo and her twins crashing.
With no OBGYN doctors available, Winston was forced to perform a C-section – his first since medical school.
But while Teddy escaped unscathed, there was bad news for another Grey Sloan doctor as a scary diagnosis was revealed.
Webber is of the last two original cast members who continues to be part of the main cast alongside Wilson’s Dr Miranda.
“This is what we do best, these horrifying, terrifying midseason finales,” Luddington said of the episode during a recent interview with TheWrap. “The script was written so well, and that being the last thing that we see, I was like, ‘Oh my god.’ The writers are just incredible.”
The show has already subjected fans to one doctor fatality this season, with Dr Monica Beltran (Natalie Morales) meeting a tragic end in the opening episode.
Grey's Anatomy airs on ABC and Hulu in the US and streams on Disney+ in the UK.
Check out more of our Drama coverage or visit our TV Guide and Streaming Guide to find out what's on. For more TV recommendations and reviews, listen to The Radio Times Podcast.
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