Vaccinated veterans who developed COVID after receiving the 2024-2025 boosters from Moderna or Pfizer/BioNTech were also less likely to visit the emergency room for complications, compared with unvaccinated COVID patients, researchers reported in The New England Journal of Medicine.
The vast majority of participants were at least 45 years old, and virtually all who received a COVID shot got one of the two approved mRNA-based vaccines that have faced renewed scrutiny from U.S. Health Secretary Robert F. Kennedy Jr., who has questioned their safety and efficacy, contrary to scientific evidence.
“The vaccines are still providing additional, not perfect, protection against meaningful outcomes, including hospitalization and death, even though such severe outcomes are now much less common overall than early in the pandemic,“ said Dr. Jesse Goodman of Georgetown Medical Center in Washington, D.C., who was not involved in the study.
The pattern was similar regardless of age or the presence of major chronic medical conditions.
Vaccination resulted in 18.3 fewer emergency department visits, 7.5 fewer hospitalizations, and 2.2 fewer deaths per 10,000 patients, they estimated.
“Given what we know about the risk of vaccination in this (middle-age and older) population, which is extremely low, these data suggest that, at least at that point when the study was performed, vaccination remained an attractive option,“ Rubin said.
Vaccine effectiveness appeared to wane modestly during the six-month study, the researchers found.
The study was not a randomized trial and so it cannot prove the COVID vaccines prevented the more severe outcomes, they noted - REUTERS
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