The Chicago Cubs (90-70) host the St. Louis Cardinals (78-82) at Wrigley Field on Saturday, beginning at 2:20 p.m. ET.
The Cubs will give the nod to Jameson Taillon (10-7) versus the Cardinals and Michael McGreevy (8-3).
Cubs vs. Cardinals Pitcher Matchup and Game Info
When: Saturday, September 27, 2025 at 2:20 p.m. ET Where: Wrigley Field in Chicago, Illinois How to watch on TV: MARQ and FDSMW Probable Pitchers: Taillon – CHC (10-7, 3.78 ERA) vs McGreevy – STL (8-3, 4.35 ERA)Cubs vs. Cardinals Odds
Cardinals to win: +140 Total: 9 runsCubs vs. Cardinals Pitcher Performance
Taillon McGreevy 22 GS 15 10-7 W-L 8-3 3.78 ERA 4.35 123.2 IP 91 25 BB 18 90 SO 55Cubs Probable Starting Pitcher: Jameson Taillon
Taillon (10-7) takes the mound for the Cubs in his 23rd start of the season. He’s put together a 3.78 ERA in 123 2/3 innings pitched, with 90 strikeouts. His most recent appearance was on Sunday against the Cincinnati Reds, when the righty went seven innings, surrendering one earned run while giving up five hits. The 33-year-old has amassed an ERA of 3.78, with 6.5 strikeouts per nine innings, in 22 games this season. Opponents are batting .228 against him. Taillon is aiming for his third straight quality start. Taillon is seeking his third straight outing lasting five or more innings. He averages 5.6 innings per appearance on the hill. In one of his 22 total appearances this season he has not allowed an earned run.Cubs vs. Cardinals Promo Codes
Cardinals Probable Starting Pitcher: Michael McGreevy
The Cardinals will send McGreevy (8-3) to the mound for his 16th start this season. The right-hander gave up five earned runs and allowed six hits in five innings pitched against the San Francisco Giants on Tuesday. The 25-year-old has an ERA of 4.35, a 3.06 strikeout-to-walk ratio and a WHIP of 1.231 in 16 games this season. In 15 starts this season, he’s earned seven quality starts. McGreevy will look to pitch five or more innings for the fourth start in a row. He has finished three appearances without allowing an earned run in 16 chances this season.How to Bet on Cubs vs. Cardinals
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