Angels vs. Royals Prediction: Expert Picks, Odds, Stats & Best Bets – Wednesday, September 24, 2025 ...Middle East

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The Los Angeles Angels (70-87) are set to take on the Kansas City Royals (79-78) Wednesday at 9:38 p.m. ET, airing on FDSW and FDSKC. The Angels are listed as -123 favorites by oddsmakers, while the underdog Royals have +103 odds for the contest.

Los Angeles’ Yusei Kikuchi gets the start, and he’ll go against Kansas City’s Stephen Kolek.

Angels vs. Royals Odds

Angels odds to win: -123 Royals odds to win: +103 Spread: Angels -1.5 Total: 8.5 runs

Angels vs. Royals Promo Codes

Game Time and Information

Date: Wednesday, September 24, 2025 Time: 9:38 p.m. ET TV: FDSW and FDSKC

Who Will Win Angels vs. Royals?

Angels and Royals Betting Trends

The Angels are 19-20 in games they were favored on the moneyline (winning 48.7% of those games).

In games it has played as moneyline favorites with odds of -123 or shorter, Los Angeles has a record of 14-15 (48.3%).

The Royals have been underdogs in 91 games this season and won 41 (45.1%) of those contests.

This season, Kansas City has won 28 of its 69 games, or 40.6%, when it’s the underdog by at least +103 on the moneyline.

In the 157 games in which bookmakers have set an over/under for the Angels, they have combined with opponents to go over the total 84 times (84-67-6).

Games involving the Royals have gone over the total set by bookmakers in 69 of 157 chances this season.

Angels Stats & Insights

The Angels rank 25th in runs scored with 659, 4.2 per game.

Los Angeles ranks fourth in MLB play with 219 home runs. They average 1.4 per game.

The Angels have the second-worst batting average in the majors (.226).

Los Angeles strikes out 10.1 times per game, the worst average in the majors.

The Angels pitching staff is 23rd in the majors with a collective eight strikeouts per nine innings.

Los Angeles has a 4.89 team ERA that ranks 28th among all MLB pitching staffs.

Royals Stats & Insights

The Royals are among the lowest scoring teams in the league, ranking 26th with just 624 total runs (four per game) this season.

Kansas City ranks 25th in Major League Baseball with 153 home runs.

The Royals’ .248 batting average ranks 15th in the league this season.

No team has fewer strikeouts this season than Kansas City, which has struck out only 6.7 times per game on average.

The Royals strike out just 7.9 batters per nine innings as a pitching staff, which ranks 26th in MLB.

Kansas City has pitched to a 3.77 ERA this season, which ranks sixth in baseball.

Angels Key Players to Watch

The Angels will send Kikuchi (6-11) to make his 33rd start of the season. He is 6-11 with a 4.05 ERA and 168 strikeouts in 173 1/3 innings pitched.

Taylor Ward leads Los Angeles in runs batted in with 102 and has a batting average of .228.

Jo Adell leads Los Angeles in home runs with 36 while driving in 96 runs and slugging .488.

Nolan Schanuel is batting .268 to lead Los Angeles, while adding 11 homers and 52 runs batted in this season.

Mike Trout has 101 hits and an OBP of .356 to go with a slugging percentage of .412 this season.

Royals Key Players to Watch

The Royals will hand the ball to Kolek (5-6) for his 19th start of the season.

Bobby Witt Jr. paces the Royals with a .293 batting average.

Maikel Garcia is hitting .288 with 38 doubles, five triples, 16 home runs and 60 walks.

Vinnie Pasquantino has accumulated a team-high 31 home runs and 108 runs batted in.

Salvador Perez has 34 doubles, 30 home runs and 26 walks while batting .242.

Angels and Royals Injuries

Angels: Zach Neto: 10 Day IL (Hand), José Soriano: 15 Day IL (Ribs), Robert Stephenson: 15 Day IL (Elbow), Tyler Anderson: 15 Day IL (Oblique), Andrew Chafin: 15 Day IL (Tricep), Anthony Rendón: 60 Day IL (Hip), Gustavo Campero: 60 Day IL (Ankle), Jorge Soler: 60 Day IL (Back), Ben Joyce: 60 Day IL (Shoulder), Carson Fulmer: 60 Day IL (Elbow), Hunter Strickland: 60 Day IL (Shoulder), Reid Detmers: 60 Day IL (Elbow), Victor Mederos: 60 Day IL (Shoulder), Travis d’Arnaud: 7 Day IL (Head)

Royals: Kyle Isbel: 10 Day IL (Hamstring), Ryan Bergert: 15 Day IL (Elbow), Hunter Harvey: 15 Day IL (Abductor), Bailey Falter: 15 Day IL (Biceps), Lucas Erceg: 15 Day IL (Shoulder), Seth Lugo: 15 Day IL (Back), Alec Marsh: 60 Day IL (Shoulder), James McArthur: 60 Day IL (Elbow), Kris Bubic: 60 Day IL (Rotator cuff)

Angels vs. Royals Prediction

Score Prediction: Royals 6, Angels 5 Total Prediction: Over 8.5 runs

How to Bet on Angels vs. Royals

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