The Los Angeles Dodgers (85-67), led by Shohei Ohtani on a two-game home run streak, are -169 favorites on the moneyline to defeat the San Francisco Giants (76-76). First pitch is set for 10:10 p.m. ET Friday, live from Dodger Stadium and airing on Apple TV+.
Clayton Kershaw will get the ball for Los Angeles while San Francisco will counter with Robbie Ray.
Dodgers vs. Giants Odds
Dodgers odds to win: -169 Giants odds to win: +142 Spread: Dodgers -1.5 Total: 8.5 runsDodgers vs. Giants Promo Codes
Game Time and Information
Date: Friday, September 19, 2025 Time: 10:10 p.m. ET TV: Apple TV+Who Will Win Dodgers vs. Giants?
Dodgers and Giants Betting Trends
The Dodgers have been the moneyline favorite 134 total times this season. They’ve finished 76-58 in those games.
Los Angeles has gone 45-32 (winning 58.4% of its games) when it has played as moneyline favorites of -169 or shorter.
This season, the Giants have won 30 out of the 64 games, or 46.9%, in which they’ve been the underdog.
This season, San Francisco has won one of its nine games, or 11.1%, when it’s the underdog by at least +142 on the moneyline.
The Dodgers have played in 152 games with a set over/under, and have combined with their opponents to go over the total 71 times (71-73-8).
The Giants and their opponents have hit the over in 71 of their 152 games with a total this season.
Dodgers Stats & Insights
The Dodgers have the No. 3 offense in baseball scoring 5.1 runs per game (778 total runs).
Los Angeles averages 1.5 home runs per game to rank second in MLB action with 225 total home runs.
The Dodgers have the fifth-best batting average in the majors (.254).
Los Angeles’ 8.3 strikeouts per game rank 16th in MLB.
The 9.2 strikeouts per nine innings compiled by the Dodgers pitching staff ranks second in MLB.
Los Angeles’ 4.05 team ERA ranks 18th among all MLB pitching staffs.
Giants Stats & Insights
The Giants have scored 662 runs (4.4 per game) this season, which ranks 17th in MLB.
San Francisco ranks 19th in Major League Baseball with 162 home runs.
The Giants have a team batting average of just .236 this season, which ranks 26th among MLB teams.
San Francisco ranks 18th in strikeouts per game (8.5) among MLB offenses.
The Giants average the 15th-most strikeouts per nine innings (8.5) in the majors this season.
San Francisco pitchers have a combined ERA of 3.85 ERA this year, 10th-best in baseball.
Dodgers Key Players to Watch
Kershaw (10-2) takes the mound for the Dodgers in his 21st start of the season. He’s put together a 3.53 ERA in 102 2/3 innings pitched, with 71 strikeouts.
Ohtani is batting .282 this season with a team-high 51 home runs and 95 RBI.
Mookie Betts is batting .261 with an OBP of .329 and a slugging percentage of .411 this season.
Freddie Freeman’s batting average of .295 leads all Los Angeles hitters this season.
Andy Pages has 151 hits and an OBP of .320 to go with a slugging percentage of .466 this season.
Giants Key Players to Watch
The Giants will hand the ball to Ray (11-7) for his 32nd start of the season.
Rafael Devers leads the Giants with 31 home runs and 103 runs batted in.
Jung Hoo Lee has a club-best .262 batting average.
Willy Adames has 20 doubles, two triples, 28 home runs and 73 walks while batting .227.
Matt Chapman is batting .235 with 20 doubles, two triples, 21 home runs and 66 walks.
Dodgers and Giants Injuries
Dodgers: Will Smith: 10 Day IL (Hand), Brock Stewart: 15 Day IL (Shoulder), Gavin Stone: 60 Day IL (Shoulder), River Ryan: 60 Day IL (Elbow), Brusdar Graterol: 60 Day IL (Shoulder), Roki Sasaki: 60 Day IL (Shoulder), Kyle Hurt: 60 Day IL (Elbow), Michael Grove: 60 Day IL (Shoulder), Tony Gonsolin: 60 Day IL (Elbow), Evan Phillips: 60 Day IL (Forearm)
Giants: Dominic Smith: 10 Day IL (Hamstring), Landen Roupp: 15 Day IL (Knee), Carson Whisenhunt: 15 Day IL (Back), Tom Murphy: 60 Day IL (Back), Randy Rodriguez: 60 Day IL (Elbow), Erik Miller: 60 Day IL (Elbow)
Dodgers vs. Giants Prediction
Score Prediction: Dodgers 5, Giants 4 Total Prediction: Over 8.5 runsHow to Bet on Dodgers vs. Giants
Get more MLB picks. If you are new to sports betting, read our in-depth guide on betting on Baseball and find the best MLB betting sites and promo codes.
Hence then, the article about dodgers vs giants prediction expert picks odds stats best bets friday september 19 2025 was published today ( ) and is available on Bleacher Nation ( Middle East ) The editorial team at PressBee has edited and verified it, and it may have been modified, fully republished, or quoted. You can read and follow the updates of this news or article from its original source.
Read More Details
Finally We wish PressBee provided you with enough information of ( Dodgers vs. Giants Prediction: Expert Picks, Odds, Stats & Best Bets – Friday, September 19, 2025 )
Also on site :