An AFP reporter saw the roof of Ukraine's cabinet of ministers in flames and smoke billowing over the capital.
Russia has shown no sign of halting its three-and-a-half-year invasion of Ukraine, pushing hardline demands for ending the war despite efforts by the United States to broker a peace deal.
The strike on Ukraine's cabinet of ministers, a sprawling government complex at the heart of Kyiv, was the first such strike of the war.
Police cordoned off the area surrounding the building.
“We will restore the buildings. But we cannot bring back lost lives. The enemy terrorises and kills our people every day throughout the country,“ she said.
Strike kills infant
A strike on a nine-story residential building in the west of Kyiv killed at least two people, a mother and her two-month-old son, prosecutors said.
Ukraine's rescue service posted photos showing the building in flames, while smoke billowed from its facade.
Kyiv says security guarantees, backed by Western troops, are crucial to any peace deal to ensure Russia does not invade again in the future.
Efforts in recent weeks by US President Donald Trump to end the war have so far yielded little progress.
Tens of thousands have been killed in three and a half years of fighting, which has forced millions from their homes and destroyed much of eastern and southern Ukraine in Europe's bloodiest conflict since World War II - AFP
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