Yankees vs. Astros Prediction: Expert Picks, Odds, Stats & Best Bets – Thursday, September 4, 2025 ...Middle East

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The New York Yankees (77-61) visit the Houston Astros (76-63) at 7:40 p.m. ET Thursday for a meeting between two of the league’s best hitters. For the favored Yankees (-148), Aaron Judge is batting .325 this year, first in the league, while Jeremy Pena ranks fifth in the majors with a .304 average for the underdog Astros.

Carlos Rodon gets the starting nod for New York while Cristian Javier is Houston’s starter for the contest.

Yankees vs. Astros Odds

Yankees odds to win: -148 Astros odds to win: +123 Spread: Yankees -1.5 Total: 9 runs

Yankees vs. Astros Promo Codes

Game Time and Information

Date: Thursday, September 4, 2025 Time: 7:40 p.m. ET TV: MLB Network, SCHN, and YES

Who Will Win Yankees vs. Astros?

Yankees and Astros Betting Trends

The Yankees have won 67 of the 116 games they were favored on the moneyline this season (57.8%).

New York has gone 48-27 (winning 64% of its games) when playing as moneyline favorites of -148 or shorter.

The Astros have been underdogs in 45 games this season and won 26 (57.8%) of those contests.

Houston has a record of 8-4 in games where sportsbooks have it as underdogs of at least +123 on the moneyline.

In the 137 games in which oddsmakers have set an over/under for the Yankees, they have combined with opponents to go over the total 66 times (66-65-6).

Games involving the Astros have gone over the total set by bookmakers in 62 of 139 chances this season.

Yankees Stats & Insights

The Yankees score the most runs in baseball (726 total, 5.3 per game).

The New York Yankees average 1.7 home runs per game and have hit an MLB-high 236 home runs in total.

The Yankees have the 12th-ranked batting average in the league (.250).

New York strikes out 8.9 times per game, the No. 24 mark in baseball.

The 9.1 strikeouts per nine innings compiled by the Yankees pitching staff ranks third in MLB.

New York has the 12th-ranked team ERA across all MLB pitching staffs (3.90).

Astros Stats & Insights

The Astros have scored the 24th-most runs in the league this season with 581 (4.2 per game).

Houston has hit 153 homers this season, which ranks 18th in the majors.

The Astros’ .252 batting average is among the best in baseball, ranking seventh in MLB.

Houston is one of the best teams in baseball at making contact this season, ranking sixth with an average of 7.9 strikeouts per game.

The Astros average 9.6 strikeouts per nine innings as a pitching staff, first-most in the big leagues.

Houston has pitched to a 3.85 ERA this season, which ranks eighth in baseball.

Yankees Key Players to Watch

Rodon makes the start for the Yankees, his 29th of the season. He is 15-7 with a 3.18 ERA and 177 strikeouts in 164 1/3 innings pitched.

Judge is batting .325 with 43 home runs and 97 RBI. All three of those stats rank first among New York hitters this season.

Cody Bellinger has 139 hits and an OBP of .332 to go with a slugging percentage of .501 this season.

Trent Grisham has 103 hits this season and a slash line of .248/.357/.484.

Jazz Chisholm has collected 92 hits this season and has an OBP of .342. He’s slugging .505 on the year.

Astros Key Players to Watch

The Astros will hand the ball to Javier (1-1) for his fifth start of the season.

Jose Altuve has collected a team-high 24 home runs.

Pena’s .304 batting average leads his team.

Yainer Diaz is batting .253 with 18 doubles, a triple, 18 home runs and 19 walks.

Christian Walker has made the most of his opportunities as he paces his team with 74 RBI.

Yankees and Astros Injuries

Yankees: Austin Slater: 10 Day IL (Hamstring), Jonathan Loaisiga: 15 Day IL (Back), Brent Headrick: 15 Day IL (Forearm), Gerrit Cole: 60 Day IL (Elbow), Oswaldo Cabrera: 60 Day IL (Ankle), Clarke Schmidt: 60 Day IL (Forearm), Jake Cousins: 60 Day IL (Elbow)

Astros: Jake Meyers: 10 Day IL (Calf), Spencer Arrighetti: 15 Day IL (Elbow), Bennett Sousa: 15 Day IL (Elbow), Josh Hader: 15 Day IL (Shoulder), Brandon Walter: 60 Day IL (Elbow), Ronel Blanco: 60 Day IL (Elbow), Zach Dezenzo: 60 Day IL (Hand), John Rooney: 60 Day IL (Concussion / nasal), Brendan Rodgers: 60 Day IL (Oblique), Isaac Paredes: 60 Day IL (Hamstring), Hayden Wesneski: 60 Day IL (Elbow), Pedro Leon: 60 Day IL (Knee)

Yankees vs. Astros Prediction

Score Prediction: Yankees 6, Astros 5 Total Prediction: Over 9 runs

How to Bet on Yankees vs. Astros

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