The St. Louis Cardinals (68-70) and Athletics (63-75) meet Tuesday at Busch Stadium, with first pitch at 7:45 p.m. ET on FDSMW and NBCS-CA. The Cardinals are -120 moneyline favorites for the contest, however, the Athletics are favored against the spread of 1.5 runs with +160 odds.
Miles Mikolas will get the ball for St. Louis while Sacramento will counter with Luis Severino.
Cardinals vs. Athletics Odds
Cardinals odds to win: -120 Athletics odds to win: +102 Spread: Athletics -1.5 Total: 8.5 runsCardinals vs. Athletics Promo Codes
Game Time and Information
Date: Tuesday, September 2, 2025 Time: 7:45 p.m. ET TV: FDSMW and NBCS-CAWho Will Win Cardinals vs. Athletics?
Cardinals and Athletics Betting Trends
The Cardinals have been the moneyline favorite 62 total times this season. They’ve gone 32-30 in those games.
The Cardinals have a record of 27-21 when they have played as a moneyline favorite with odds of -120 or shorter (56.2%).
This season, the Athletics have been the underdog 105 times and won 47, or 44.8%, of those games.
The Athletics have a record of 38-56, a 40.4% win rate, when they’re set as the underdog by +102 or more by oddsmakers this season.
The Cardinals have combined with their opponents to go over the total 70 times this season for a 70-60-7 record against the over/under.
The Athletics and their opponents have hit the over in 68 of their 138 games with a total this season.
Cardinals Stats & Insights
The Cardinals are the 16th-highest scoring team in MLB action averaging 4.4 runs per game (603 total).
The Cardinals average one home run per game to rank 25th in MLB action with 132 total home runs.
The Cardinals are 16th in the majors with a .247 batting average.
The Cardinals strike out 8 times per game, the ninth-best mark in MLB.
The pitching staff for the Cardinals has a collective 7.6 K/9, the second-worst in the majors.
The Cardinals have a 4.27 team ERA that ranks 21st across all league pitching staffs.
Athletics Stats & Insights
The Athletics have scored 625 runs (4.5 per game) this season, which ranks 12th in MLB.
The Athletics rank seventh in Major League Baseball with 187 home runs.
The Athletics have a team batting average of .253 this season, which ranks fourth among MLB teams.
The Athletics rank 22nd with an average of 8.6 strikeouts per game.
The Athletics strike out 8.3 batters per nine innings as a pitching staff, 20th in MLB.
The Athletics have pitched to a 4.84 ERA this season, which ranks 28th in baseball.
Cardinals Key Players to Watch
The Cardinals are sending Mikolas (6-10) out to make his 27th start of the season. He is 6-10 with a 5.04 ERA and 86 strikeouts in 130 1/3 innings pitched.
Willson Contreras leads St. Louis in home runs (20) and runs batted in (74) this season while batting .253.
Masyn Winn has collected 120 hits this season and has an OBP of .311. He’s slugging .370 on the year.
Lars Nootbaar is slashing .239/.330/.387 this season for the Cardinals.
Ivan Herrera is batting .286 with an OBP of .367 and a slugging percentage of .432 this season.
Athletics Key Players to Watch
The Athletics’ Severino (6-11) will make his 25th start of the season.
Brent Rooker has put up a team-best 79 runs batted in.
Tyler Soderstrom is hitting .270 with 27 doubles, a triple, 23 home runs and 51 walks.
Shea Langeliers has collected a team-high 29 home runs.
Nick Kurtz is hitting .308 with 23 doubles, two triples, 27 home runs and 53 walks.
Cardinals and Athletics Injuries
Cardinals: Alec Burleson: 10 Day IL (Wrist), Nolan Arenado: 10 Day IL (Shoulder), Brendan Donovan: 10 Day IL (Groin), John King: 15 Day IL (Back), Zack Thompson: 60 Day IL (Lat), Yohel Pozo: 7 Day IL (Concussion)
Athletics: Denzel Clarke: 10 Day IL (Abductor), Max Muncy: 10 Day IL (Hand), Joey Estes: 15 Day IL (Back), Jacob Lopez: 15 Day IL (Flexor), Jack Perkins: 15 Day IL (Shoulder), Luis Medina: 60 Day IL (Elbow), Ben Bowden: 60 Day IL (Lat), Austin Wynns: 60 Day IL (Abdomen), Grant Holman: 60 Day IL (Shoulder), Gunnar Hoglund: 60 Day IL (Hip), Jose Leclerc: 60 Day IL (Shoulder)
Cardinals vs. Athletics Prediction
Score Prediction: Cardinals 6, Athletics 5 Total Prediction: Over 8.5 runsHow to Bet on Cardinals vs. Athletics
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