Following a two-homer game in a win over the Cubs, Willy Adames leads the San Francisco Giants (66-68) into action as -159 favorites against the Baltimore Orioles (60-74). First pitch from Oracle Park at 10:15 p.m. ET on Friday, live on Apple TV+.
San Francisco’s Robbie Ray and Baltimore’s Dean Kremer have been named the starters for this contest.
Giants vs. Orioles Odds
Giants odds to win: -159 Orioles odds to win: +134 Spread: Giants -1.5 Total: 7.5 runsGiants vs. Orioles Promo Codes
Game Time and Information
Date: Friday, August 29, 2025 Time: 10:15 p.m. ET TV: Apple TV+Who Will Win Giants vs. Orioles?
Giants and Orioles Betting Trends
The Giants have put together a 39-38 record in games they were favored on the moneyline (winning 50.6% of those games).
San Francisco has a 15-15 record (winning 50% of its games) when playing as moneyline favorites of -159 or shorter.
The Orioles have entered the game as underdogs 72 times this season and won 32, or 44.4%, of those games.
Baltimore has entered 17 games this season as the underdog by +134 or more and is 5-12 in those contests.
The Giants have combined with opponents to go over the total 60 times this season for a 60-66-8 record against the over/under.
So far this season, the Orioles and their opponents have hit the over in 56 of their 134 games with a total.
Giants Stats & Insights
The Giants are the 25th-highest scoring team in MLB action averaging 4.1 runs per game (551 total).
San Francisco ranks 20th in baseball with 136 total home runs.
The Giants’ .233 batting average ranks 27th in MLB.
San Francisco’s 8.6 strikeouts per game rank 20th in MLB.
The 8.5 strikeouts per nine innings put together by the Giants pitching staff ranks 14th in the majors.
San Francisco has the sixth-ranked team ERA among all MLB pitching staffs (3.70).
Orioles Stats & Insights
The Orioles have scored the 17th-most runs in the league this season with 574 (4.3 per game).
Baltimore’s 160 home runs rank 13th in Major League Baseball.
The Orioles’ .240 batting average ranks 22nd in the league this season.
Baltimore ranks 21st in strikeouts per game (8.7) among MLB offenses.
The Orioles average the 16th-most strikeouts per nine innings (8.4) in the majors this season.
Baltimore has pitched to a 4.67 ERA this season, which ranks 26th in baseball.
Giants Key Players to Watch
Ray (10-6) takes the mound for the Giants in his 28th start of the season. He has a 2.93 ERA in 159 2/3 innings pitched, with 158 strikeouts.
Rafael Devers leads San Francisco in home runs with 27 and runs batted in with 89.
Jung Hoo Lee has 125 hits and an OBP of .323 to go with a slugging percentage of .409 this season.
Adames has 110 hits this season and a slash line of .224/.313/.415.
Heliot Ramos leads San Francisco with a batting average of .265. He’s also hit 16 home runs with 57 RBI.
Orioles Key Players to Watch
The Orioles’ Kremer (9-9) will make his 26th start of the season.
Gunnar Henderson paces the Orioles in home runs (16), runs batted in (59) and has accumulated a team-best batting average of .277.
Jackson Holliday is hitting .242 with 18 doubles, two triples, 15 home runs and 38 walks.
Colton Cowser is batting .219 with 11 doubles, 12 home runs and 17 walks.
Ryan Mountcastle has 14 doubles, four home runs and 11 walks while hitting .251.
Giants and Orioles Injuries
Giants: Jerar Encarnación: 10 Day IL (Hamstring), Landen Roupp: 15 Day IL (Knee), Randy Rodriguez: 15 Day IL (Elbow), Tom Murphy: 60 Day IL (Back), Erik Miller: 60 Day IL (Elbow)
Orioles: Jordan Westburg: 10 Day IL (Ankle), Tyler O’Neill: 10 Day IL (Wrist), Adley Rutschman: 10 Day IL (Oblique), Colin Selby: 15 Day IL (Hamstring), Felix Bautista: 60 Day IL (Shoulder), Jorge Mateo: 60 Day IL (Elbow), Scott Blewett: 60 Day IL (Elbow), Albert Suarez: 60 Day IL (Shoulder), Zach Eflin: 60 Day IL (Back), Cody Poteet: 60 Day IL (Shoulder), Grayson Rodriguez: 60 Day IL (Elbow), Tyler Wells: 60 Day IL (Elbow), Brandon Young: 60 Day IL (Hamstring), Gary Sánchez: 60 Day IL (Knee)
Giants vs. Orioles Prediction
Score Prediction: Giants 4, Orioles 3 Total Prediction: Under 7.5 runsHow to Bet on Giants vs. Orioles
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