The San Francisco Giants (61-67) will try to end their three-game losing streak when they visit the Milwaukee Brewers (80-48) on Friday at 8:10 p.m. ET on FDSWI and NBCS-BA. Sportsbooks consider the Brewers to be -158 favorites for the contest, while the Giants are +134 underdogs looking for the upset.
Milwaukee’s Jose Quintana gets the start, and he’ll go against San Francisco’s Carson Whisenhunt.
Brewers vs. Giants Odds
Brewers odds to win: -158 Giants odds to win: +134 Spread: Brewers -1.5 Total: 8.5 runsBrewers vs. Giants Promo Codes
Game Time and Information
Date: Friday, August 22, 2025 Time: 8:10 p.m. ET TV: FDSWI and NBCS-BAWho Will Win Brewers vs. Giants?
Brewers and Giants Betting Trends
The Brewers have won 69.1% of the games this season when they were the moneyline favorite (47-21).
In games it has played as moneyline favorites with odds of -158 or shorter, Milwaukee has gone 14-6 (70%).
The Giants have won 23, or 45.1%, of the 51 games they’ve played as underdogs this season.
This season, San Francisco has won four of its 13 games, or 30.8%, when it’s the underdog by at least +134 on the moneyline.
The Brewers have played in 128 games with set over/under, and have combined with opponents to go over the total 60 times (60-64-4).
The Giants’ games have gone over the total in 58 of their 128 chances.
Brewers Stats & Insights
The Brewers have the No. 2 offense in MLB play scoring 5.1 runs per game (657 total runs).
Milwaukee is 18th in MLB play with 136 home runs. They average 1.1 per game.
The Brewers are second in the majors with a .258 batting average.
Milwaukee strikes out 7.9 times per game to rank eighth in MLB.
The 8.8 strikeouts per nine innings put together by the Brewers pitching staff ranks seventh in the majors.
Milwaukee has the third-ranked team ERA across all MLB pitching staffs (3.57).
Giants Stats & Insights
The Giants have scored the 25th-most runs in the league this season with 515 (four per game).
San Francisco ranks 25th in Major League Baseball with 123 home runs.
The Giants have a team batting average of just .231 this season, which ranks 28th among MLB teams.
San Francisco ranks 21st with an average of 8.6 strikeouts per game.
The Giants have an 8.6 K/9 this season as a pitching staff, which ranks 12th in the majors.
San Francisco has the eighth-best ERA (3.77) in the majors this season.
Brewers Key Players to Watch
The Brewers will send Quintana (10-4) out for his 20th start of the season. He is 10-4 with a 3.32 ERA and 73 strikeouts through 105 2/3 innings pitched.
Christian Yelich is batting .262 this season with a team-high 26 home runs and 87 RBI.
Brice Turang is batting .286 with an OBP of .350 and a slugging percentage of .429 this season.
William Contreras has 118 hits this season and a slash line of .256/.355/.388.
Sal Frelick leads Milwaukee with a .300 batting average. He’s also hit nine homers and has 49 RBI.
Giants Key Players to Watch
The Giants will send Whisenhunt to the mound for his first start this season.
Rafael Devers leads the Giants with 25 home runs and 83 runs batted in.
Jung Hoo Lee is batting .262 with 29 doubles, 10 triples, seven home runs and 40 walks.
Willy Adames is batting .222 with 18 doubles, two triples, 20 home runs and 60 walks.
Heliot Ramos has a club-leading .263 batting average.
Brewers and Giants Injuries
Brewers: Jackson Chourio: 10 Day IL (Hamstring), Jake Bauers: 10 Day IL (Shoulder), Rhys Hoskins: 10 Day IL (Thumb), Logan Henderson: 15 Day IL (Elbow), Rob Zastryzny: 15 Day IL (Ribs), D.L. Hall: 15 Day IL (Oblique), Robert Gasser: 60 Day IL (Elbow), Garrett Mitchell: 60 Day IL (Oblique), Connor Thomas: 60 Day IL (Elbow), Jordan Montgomery: 60 Day IL (Elbow), Joey Ortiz: day-to-day (Hamstring)
Giants: Matt Chapman: 10 Day IL (Hand), Jerar Encarnación: 10 Day IL (Hamstring), Tom Murphy: 60 Day IL (Back), Erik Miller: 60 Day IL (Elbow), Landen Roupp: day-to-day (Leg)
Brewers vs. Giants Prediction
Score Prediction: Brewers 5, Giants 3 Total Prediction: Under 8.5 runsHow to Bet on Brewers vs. Giants
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