The San Diego Padres (69-54) are -130 favorites to break their two-game losing streak when they face the San Francisco Giants (59-64), losers of seven in a row. The game begins Monday at 9:40 p.m. ET on SDPA and NBCS-BA, live from PETCO Park.
Nestor Cortes gets the starting nod for San Diego while Robbie Ray is San Francisco’s starter for the contest.
Padres vs. Giants Odds
Padres odds to win: -130 Giants odds to win: +110 Spread: Padres -1.5 Total: 8 runsPadres vs. Giants Promo Codes
Game Time and Information
Date: Monday, August 18, 2025 Time: 9:40 p.m. ET TV: SDPA and NBCS-BAWho Will Win Padres vs. Giants?
Padres and Giants Betting Trends
The Padres are 40-26 in games they were favored on the moneyline (winning 60.6% of those games).
San Diego has a 33-20 record (winning 62.3% of its games) when playing as moneyline favorites of -130 or shorter.
This season, the Giants have been the underdog 47 times and won 22, or 46.8%, of those games.
San Francisco has a record of 12-16, a 42.9% win rate, when it’s set as an underdog of +110 or more by bookmakers this season.
The Padres have played in 123 games with set over/under, and have combined with opponents to go over the total 50 times (50-68-5).
So far this season, the Giants and their opponents have hit the over in 55 of their 123 games with a total.
Padres Stats & Insights
The Padres are the 24th-highest scoring team in MLB action averaging 4.2 runs per game (511 total).
San Diego has hit the second-fewest home runs in MLB action this season (104).
The Padres have the eighth-best batting average in the majors (.251).
San Diego strikes out 6.9 times per game, the second-best average in the majors.
The pitching staff for the Padres has a collective 8.7 K/9, the eighth-best in the majors.
San Diego has a 3.58 team ERA that ranks second across all MLB pitching staffs.
Giants Stats & Insights
The Giants rank 25th in the majors with 498 total runs scored this season.
San Francisco ranks 27th in Major League Baseball with just 114 home runs as a team.
The Giants have a team batting average of just .232 this season, which ranks 26th among MLB teams.
San Francisco ranks 18th with an average of 8.5 strikeouts per game.
The Giants have an 8.6 K/9 this season as a pitching staff, which ranks 12th in the big leagues.
San Francisco has pitched to a 3.75 ERA this season, which ranks fifth in baseball.
Padres Key Players to Watch
Cortes makes the start for the Padres, his fifth of the season. He is 1-1 with a 5.71 ERA and 17 strikeouts in 17 1/3 innings pitched.
Manny Machado leads San Diego in home runs with 20, runs batted in with 72 and his batting average of .294 is also best on his team.
Fernando Tatis Jr. has collected 122 hits this season and has an OBP of .372. He’s slugging .435 on the year.
Luis Arraez is slashing .288/.324/.393 this season for the Padres.
Xander Bogaerts has 117 hits and an OBP of .333 to go with a slugging percentage of .395 this season.
Giants Key Players to Watch
The Giants will send Ray (9-6) to the mound for his 26th start this season.
Rafael Devers leads the Giants in home runs (23) and runs batted in (81).
Jung Hoo Lee is hitting .260 with 27 doubles, 10 triples, six home runs and 39 walks.
Willy Adames is hitting .224 with 18 doubles, two triples, 19 home runs and 56 walks.
Heliot Ramos has a club-high .265 batting average.
Padres and Giants Injuries
Padres: Michael King: 15 Day IL (Knee), Jhony Brito: 60 Day IL (Forearm), Joe Musgrove: 60 Day IL (Elbow), Jackson Merrill: day-to-day (Undisclosed)
Giants: Matt Chapman: 10 Day IL (Hand), Jerar Encarnación: 10 Day IL (Hamstring), Erik Miller: 15 Day IL (Elbow), Tom Murphy: 60 Day IL (Back)
Padres vs. Giants Prediction
Score Prediction: Padres 5, Giants 4 Total Prediction: Over 8 runsHow to Bet on Padres vs. Giants
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