Padres vs. Diamondbacks Prediction: Expert Picks, Odds, Stats & Best Bets – Tuesday, August 5, 2025 ...Middle East

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Luis Arraez will look to extend his 16-game hitting streak when the San Diego Padres (62-50) take on the Arizona Diamondbacks (53-59). The Padres are listed as -136 favorites on the moneyline for the contest, which starts at 9:40 p.m. ET on Tuesday, live on MLB Network, ARID, and SDPA from Chase Field.

Yu Darvish will get the ball for San Diego while Arizona will counter with Ryne Nelson.

Padres vs. Diamondbacks Odds

Padres odds to win: -136 Diamondbacks odds to win: +115 Spread: Padres -1.5 Total: 9 runs

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Game Time and Information

Date: Tuesday, August 5, 2025 Time: 9:40 p.m. ET TV: MLB Network, ARID, and SDPA

Who Will Win Padres vs. Diamondbacks?

Padres and Diamondbacks Betting Trends

The Padres have won 59.3% of the games this season when they were the moneyline favorite (35-24).

San Diego has a 23-15 record (winning 60.5% of its games) when it has played as moneyline favorites of -136 or shorter.

The Diamondbacks have won 19, or 44.2%, of the 43 games they’ve played as underdogs this season.

This season, Arizona has won 12 of its 20 games, or 60%, when it’s the underdog by at least +115 on the moneyline.

In the 112 games in which oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 45 times (45-62-5).

The Diamondbacks’ games have gone over the total in 53 of their 111 chances.

Padres Stats & Insights

The Padres are the 25th-highest scoring team in MLB play averaging 4.1 runs per game (461 total).

San Diego has hit 95 home runs this season, the second-lowest total in baseball.

The Padres have the 11th-ranked batting average in the league (.251).

San Diego strikes out seven times per game to rank third in the majors.

The pitching staff for the Padres has a collective 8.7 K/9, the seventh-best in the majors.

San Diego has a 3.58 team ERA that ranks third among all MLB pitching staffs.

Diamondbacks Stats & Insights

The Diamondbacks are among the highest scoring teams in the majors, ranking seventh with 542 total runs this season.

Arizona has hit 153 homers this season, which ranks sixth in the majors.

The Diamondbacks rank 14th in MLB with a .249 team batting average.

Arizona is one of the best teams in baseball at making contact this season, ranking eighth with an average of 7.9 strikeouts per game.

The Diamondbacks have an 8.4 K/9 this season as a pitching staff, which ranks 16th in the majors.

Arizona has the 25th-ranked ERA (4.57) in the majors this season.

Padres Key Players to Watch

Darvish makes the start for the Padres, his sixth of the season. He is 1-3 with a 6.46 ERA and 18 strikeouts in 23 2/3 innings pitched.

Manny Machado leads San Diego in batting average (.299), home runs (20) and runs batted in (72) this season.

Fernando Tatis Jr. is batting .264 with an OBP of .367 and a slugging percentage of .442 this season.

Arraez is slashing .298/.333/.407 this season for the Padres.

Xander Bogaerts has collected 107 hits this season and has an OBP of .339. He’s slugging .383 on the year.

Diamondbacks Key Players to Watch

The Diamondbacks will hand the ball to Nelson (6-3) for his 14th start of the season.

Geraldo Perdomo has sent home a team-high 75 runs batted in.

Corbin Carroll has hit 22 home runs to lead his team.

Ketel Marte has racked up a team-high batting average of .288.

Lourdes Gurriel Jr. has 21 doubles, two triples, 12 home runs and 26 walks while hitting .244.

Padres and Diamondbacks Injuries

Padres: Jhony Brito: 60 Day IL (Forearm), Michael King: 60 Day IL (Shoulder), Joe Musgrove: 60 Day IL (Elbow)

Diamondbacks: Ildemaro Vargas: 10 Day IL (Foot), Pavin Smith: 10 Day IL (Oblique), Ryan Thompson: 15 Day IL (Scapular strain), Kevin Ginkel: 15 Day IL (Shoulder), Blake Walston: 60 Day IL (Elbow), Corbin Burnes: 60 Day IL (Elbow), Gabriel Moreno: 60 Day IL (Hand), A.J. Puk: 60 Day IL (Elbow), Christian Montes De Oca: 60 Day IL (Elbow), Cristian Mena: 60 Day IL (Shoulder), Justin Martinez: 60 Day IL (Elbow), Tommy Henry: 60 Day IL (Elbow)

Padres vs. Diamondbacks Prediction

Score Prediction: Diamondbacks 5, Padres 4 Total Prediction: Under 9 runs

How to Bet on Padres vs. Diamondbacks

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