When it comes to Season 11, his plan is “to take everything a step further but still be on the same path,” he told Parade. “I told the writers that in every episode [of Season 10], I want everyone to cry in every episode, and I want everybody to laugh in every episode. I want to continue that emotional torture for the audience as much as I possibly can, but take the characters in different directions.”
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With that tease, and more below, here’s what we know about Season 11 of Chicago Med:
What time will Chicago Med Season 11 be on?
When Chicago Med returns for its 11th season on Oct. 1, it will be back in its Wednesday night at 8 p.m. ET/PT timeslot.
Related: Chicago Med Boss Teases Layoffs and Baby Drama in Season 10 Finale (Exclusive)
Who is in the cast of Chicago Med Season 11?
S. Epatha Merkerson
S. Epatha Merkerson as Sharon Goodwin on 'Chicago Med'Photo by: George Burns Jr/NBC
Merkerson plays Sharon Goodwin, the chief administrator of Gaffney Chicago Medical Center.
Oliver Platt
Oliver Platt as Daniel Charles on 'Chicago Med'Photo by: Elizabeth Sisson/NBC
Platt plays Dr. Daniel Charles, chief of the psychiatry department.
Marlyne Barrett
Marlyne Barrett as Maggie Lockwood on 'Chicago Med'Photo by: George Burns Jr/NBC
Barrett plays Maggie Lockwood, charge nurse of the emergency department.
Steven Weber
Steven Weber as Dean Archer on 'Chicago Med'Photo by: George Burns Jr/NBC
Weber plays Dr. Dean Archer, the former head of the ED (Emergency Department).
Jessy Schram
Jessy Schram as Hannah Asher on 'Chicago Med'Photo by: George Burns Jr/NBC
Schram plays Dr. Hannah Asher, a Board-Certified Obstetrician-Gynecologist and recovering addict.
Luke Mitchell
Luke Mitchell as Mitch Ripley on 'Chicago Med'Photo by: Elizabeth Sisson/NBC
Mitchell plays Dr. Mitch Ripley, an attending physician in the Emergency Department.
Sarah Ramos
Sarah Ramos as Caitlin Lenox on 'Chicago Med'Photo by: James Washington/NBC
Ramos plays Dr. Caitlin Lenox, the head of the ED.
Darren Barnet
Darren Barnet as John Frost on 'Chicago Med'Photo by: George Burns Jr/NBC
Barnet plays Dr. John Frost, a pediatric resident.
Who is leaving Chicago Med in Season 11?
John Earl Jelks as Dr. Dennis Washington
John Earl Jelks as Dennis Washington and S. Epatha Merkerson as Sharon Goodwin on 'Chicago Med'Photo by: George Burns Jr/NBC
Washington was written out as part of the budget-cut storyline. Sharon Goodwin tried to renegotiate his deal, but his ego wouldn’t stand for it and he resigned.
Ashlei Sharpe Chestnut as Dr. Naomi Howard
Ashlei Sharpe Chestnut as Naomi Howard on 'Chicago Hope'Photo by: George Burns Jr/NBC
The Season 10 finale was jammed packed. Sharon Goodwin (S. Epatha Merkerson) was once again tasked with making cuts to hospital personnel, and interestingly, one of the cuts was her boyfriend Dennis Washington.
Dr. Daniel Charles’ mother died unexpectedly while visiting the hospital, and her funeral did see the return of Dr. Charles’ two daughters, Anna (Hannah Riley) and Robin (Mekia Cox). Anna is having some major issues, and Dr. Charles learned in the finale that he wasn’t as successful at parenting that he thought he was.
Related: Chicago Med’s Bombshell Update on Hannah’s Pregnancy Is Turning Heads
Are there any spoilers for Chicago Med Season 11?
“With Lenox, she's lived her whole life with this deadly disease hanging over her head that she had the security of not knowing for sure, now she knows for sure she has it. She's going to die young. Whether that's in 10, 12 or 15 years, we don't know. I think Lenox is going to start viewing her life differently and making decisions differently ,and her brother, too, by the way because now he knows he's OK."
For Dr. Charles, his situation will see him more involved with his family. His daughters, Anna and Robin, returned for their grandmother’s funeral. But MacDonald teases that Anna will stay around.
An official trailer for Chicago Med Season 11 has yet to be released but check back here. We will post as soon as it’s available.
How to watch Chicago Med
All 10 seasons of Chicago Med are available on streaming service Peacock. Previous seasons are also available on Amazon Prime and IMDBTV.
How many seasons of Chicago Med are there?
Related: NBC Announces Its Fall 2025-2026 Schedule
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