During a June 2025 interview with People magazine, Ackles referenced that Dane revealed he was diagnosed with ALS (Amyotrophic Lateral Sclerosis) in April 2025. Ackles, who plays Detective Mark Meachum on the Amazon Prime show, described Dane as "an incredible human being."
In addition, he said Dane is in "fight, not flight" amid his health battle.
Ackles and Dane, who plays Special Agent Nathan Blythe, discussed their friendship during a joint June 2025 interview with Entertainment Tonight. Ackles said he was "nervous" and "excited" to co-star alongside the 52-year-old because he had "known of him for many, may years."
Dane agreed with his co-star's assessment about their dynamic. In addition, he said the entire Countdown cast has good chemistry. Dane also said Countdown has been "a welcomed distraction" following his ALS diagnosis.
"It's also kept me moving forward. It gives me a sense of purpose. And I love going to work with these people. So that's an added bonus," said the father of two.
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