Andrei Vorobyov, governor of the Moscow region, said the drone started a fire on the 17th floor of the building in the town of Krasnogorsk, west of the capital. The injured people were receiving treatment at a hospital.
Moscow Mayor Sergei Sobyanin said earlier that Russian air defences had intercepted two Ukrainian drones heading for the city overnight.
The mayor said a third drone targeting the capital had been repelled earlier in the evening.
Ukraine has launched drone attacks on a wide range of targets in recent months, some a long distance from the Ukrainian border.
In recent months, Russia has stepped up mass drone attacks against Ukrainian cities. Waves of Russian drones and missiles swarming in and around Kyiv killed 10 people overnight on Sunday
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