Can COVID-19 vaccines be mixed and matched? Health officials say both doses should be of the same vaccine. The COVID-19 vaccines rolling out in the United States, the United Kingdom and other parts of the world so far require two shots given a few weeks apart. In the U.S. where Pfizer and Moderna vaccines are being distributed, health officials say the vaccines are not interchangeable. In England where shots by Pfizer and AstraZeneca are available, officials also say the doses should be consistent. But in the rare event that the same kind isn’t available or if it’s not known what was given for the first shot, English officials say it’s OK to give whichever vaccine is available for the second
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