Cellular exclusion of mitochondria protects cells from damage ...Middle East

Researchers from Osaka University identified mitochondrial release out of cells as a novel mechanism by which cells turn over mitochondria and maintain cell health. The researchers found that cells deficient in the protein parkin, which is responsible for the hereditary form of Parkinson's disease (PD), showed markedly increased mitochondrial release. Further, cerebrospinal fluids of PD patients with a mutation in parkin contained elevated levels of mitochondria. This study could help develop new biomarkers and therapeutics.

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