Study explains why treatments for autoimmune, inflammatory diseases raise TB risk  ...Middle East

New Delhi, Sep 1 (IANS) Researchers have found how a protein produced by immune cells and used to treat autoimmune and inflammatory diseases raises the risk of tuberculosis (TB). While TB is the leading cause of mortality from infectious disease in the world, the deaths represent just 5 per cent of infections with Mycobacterium tuberculosis (Mtb). Mtb spreads through the air and usually infects the lungs. Researchers have long known that an acquired deficiency of “tumour necrosis factor” (TNF) can raise the risk of developing TB. Upending long-held assumptions about the immune system, the study, published in the journal Nature, revealed that a lack of TNF incapacitates a specific immune proc

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