New Delhi, Aug 7 (IANS) Donor-derived cell-free DNA (dd-cfDNA), also known as liquid biopsy, has the potential for early detection of kidney transplant rejection, a new study shows. The international study enrolled kidney transplant recipients – both adult and paediatric – from 14 transplantation centres in Europe and the US. In inflammation associated with transplant rejection, dying cells release donor-derived cell-free DNA (dd-cfDNA) into the bloodstream. Researchers found that dd-cfDNA levels were strongly correlated with different types of transplant rejection, including antibody-mediated rejection, T cell-mediated rejection, and mixed rejection. The study found similar accuracy in both
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