Metformin use was associated with improved survival in patients with ovarian cancer, according to a study published in Neoplasia.1 Metformin is widely used as a first-line therapy in patients with type 2 diabetes to normalize hyperglycemia.2 Past studies have associated metformin use with a reduced risk of cancer in patients with diabetes.1 Other studies suggested that metformin use after diagnosis may improve survival in patients with ovarian cancer. However, the findings of past studies on the impact of metformin use on survival in patients with ovarian cancer are inconsistent. The researchers noted that many of these studies suffered from immortal time bias, which is a bias that occurs
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