San Francisco, June 15 (IANS) Scientists have reported an innovative gene-based treatment that modifies a patient’s own blood-forming stem cells to correct the mutation responsible for sickle cell disease. The clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options. The 18 patients, two of whom were treated at Cleveland Clinic Children’s in the US, underwent a procedure where their stem cells were first collected for gene editing. The trial was conducted as part of the multi-centre ‘RUBY Trial.’ They received chemotherapy to clear remaining bone marrow, making room for the repaired cells which were later infused back
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