Although infections can induce a number of symptoms, one common symptom is the loss of fat and muscle, a process known as wasting. Salk researchers wanted to know if wasting may help them fight diseases. Researchers in Professor Janelle Ayres’ lab discovered the wasting response to T brucei infection in mice occurs in two phases, each regulated by different immune cells. While fat loss did not benefit the fight against infection, muscle loss did—a surprising clue that some wasting may help manage illness.
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